Selank
A synthetic analog of tuftsin, studied for anxiolytic-like activity and immune-peptide signaling.
Overview
Selank is a synthetic peptide developed in Russia, structurally based on tuftsin, a naturally occurring immunomodulatory peptide fragment of the antibody IgG. Like Semax, it emerged from Russian neuropharmacology research programs and has been studied primarily via the intranasal research route.
Mechanism of Action
Selank has been studied for anxiolytic-like (anxiety-modulating) effects in animal behavioral models, alongside immune-modulating activity inherited from its tuftsin-based structure. Proposed mechanisms include modulation of GABAergic signaling and influence on the activity of enzymes involved in enkephalin degradation, though the complete mechanistic picture remains an active area of research.
Cited Research
Anxiolytic-behavior animal models
Studied in rodent behavioral paradigms designed to measure anxiety-related responses.
Tuftsin-derived immune research
Examined immune-modulating properties inherited from Selank’s tuftsin-based structure.
Enzyme-activity research
Investigated Selank’s effect on enkephalinase enzyme activity as a proposed mechanism.
Comparative neuropeptide studies
Frequently studied alongside Semax as part of a broader Russian research program on synthetic regulatory peptides.
This is a summary, not an exhaustive review. Search the primary literature yourself: Selank on PubMed →
Safety & Handling
Selank should be handled only by qualified personnel in a laboratory setting, stored and reconstituted per its Certificate of Analysis, and kept refrigerated once reconstituted. It is not evaluated or approved by the FDA for any human or veterinary use.
Frequently Asked Questions
Is Selank legal to purchase?
It’s legal to sell and purchase as a research chemical for laboratory use in the U.S. It is not approved by the FDA as a drug or supplement for human consumption.
How is Selank different from Semax?
Both are Russian-developed neuropeptides often studied together, but they have distinct structures and origins — Selank is tuftsin-derived and studied mainly for anxiolytic and immune activity, while Semax is ACTH-derived and studied mainly for neurotrophic and cognitive signaling.
How should Selank be stored?
Keep refrigerated or frozen and protected from light prior to use. Follow the handling window indicated on its Certificate of Analysis once prepared for an experimental protocol.
Is this page medical advice?
No. This page summarizes published literature for research and educational context only. It does not recommend a dose, protocol, or use in humans or animals outside a laboratory setting.
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