Tesamorelin
A stabilized GHRH analog — among the most clinically studied compounds in this category — researched for visceral fat and GH-axis signaling.
Overview
Tesamorelin is a synthetic analog of growth-hormone-releasing hormone (GHRH) with structural modifications that improve its stability compared to natural GHRH. It’s notable among research peptides for having an approved pharmaceutical version in certain countries for a specific clinical indication, making it one of the more clinically studied compounds in this category. The research-grade material Stack Science sells is a distinct, unapproved product intended strictly for laboratory research.
Mechanism of Action
Like other GHRH analogs, Tesamorelin binds GHRH receptors in the pituitary gland, stimulating the body’s natural pulsatile release of growth hormone. Its approved-use research focus has centered on visceral adipose tissue (deep abdominal fat) reduction, and it has been studied for downstream effects on IGF-1 levels and body composition.
Cited Research
Visceral fat reduction trials
The primary approved-use research base examining Tesamorelin’s effect on visceral adipose tissue.
IGF-1 / GH-axis pharmacokinetics
Characterized dose-response relationships between Tesamorelin administration and IGF-1 elevation.
Body-composition research
Studied across multiple patient populations for effects on lean mass and fat distribution.
GHRH-analog stability research
Documents the structural modifications that extend Tesamorelin’s stability relative to native GHRH.
This is a summary, not an exhaustive review. Search the primary literature yourself: Tesamorelin on PubMed →
Safety & Handling
The research-grade Tesamorelin sold by Stack Science should be handled only by qualified personnel in a laboratory setting, stored and reconstituted per its Certificate of Analysis, and kept refrigerated once reconstituted. It is not the FDA-approved pharmaceutical product and is not intended for human use in this form.
Frequently Asked Questions
Is Tesamorelin FDA approved?
An approved pharmaceutical version exists in certain countries for a specific clinical indication (reduction of visceral fat in a defined patient population). However, the research-grade material sold here is a separate, unapproved product intended strictly for laboratory research, not human use.
Is Tesamorelin legal to purchase for research?
Yes, the research-grade compound is legal to sell and purchase for laboratory research purposes in the U.S.
How should it be stored?
Keep the lyophilized powder refrigerated or frozen prior to reconstitution. Once reconstituted, keep refrigerated and use within the timeframe on its Certificate of Analysis.
Is this page medical advice?
No. This page summarizes published literature for research and educational context only. It does not recommend a dose, protocol, or use in humans or animals outside a laboratory setting.
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